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Context Info
Confidence 0.03
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (TRAFD1)
TRAFD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 56.20 Quite High
substance P 3 51.56 Quite High
bradykinin 1 50.44 Quite High
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 1 100.00 Very High Very High Very High
Cancer 58 89.28 High High
Disorders Of Galactose Metabolism 1 81.28 Quite High
Disease Progression 2 77.04 Quite High
Carcinosarcoma 1 75.20 Quite High
Colon Cancer 1 67.64 Quite High
Sarcoma 2 65.16 Quite High
Apoptosis 33 50.00 Quite Low
Malignant Neoplastic Disease 9 50.00 Quite Low
Metastasis 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
p16 specifically inhibits the cyclin D1-CDK4/6 complex and, along with the main substrate, forms the retinoblastoma gene product (pRb), which is the most important regulatory pathway involved in the G1/S transition [45,46].
retinoblastoma gene product Binding (forms) of associated with retinoblastoma
1) Confidence 0.03 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2913917 Disease Relevance 0.85 Pain Relevance 0
They are identical with the sequences of the two chains of lysosomal "protective protein" which, in turn, has sequence similarity to the KEX1 gene product and carboxypeptidase Y of yeast.
KEX1 gene product Binding (similarity) of
2) Confidence 0.02 Published 1990 Journal J. Biol. Chem. Section Abstract Doc Link 1694176 Disease Relevance 0.08 Pain Relevance 0.11

General Comments

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