INT144509

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.91
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 1
spinal cord dorsal horn 1
Scq1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 52 100.00 Very High Very High Very High
Dorsal horn 7 100.00 Very High Very High Very High
GABAergic 6 100.00 Very High Very High Very High
spinal dorsal horn 5 100.00 Very High Very High Very High
nMDA receptor 3 100.00 Very High Very High Very High
Pain 2 95.36 Very High Very High Very High
Stimulus evoked pain 1 94.76 High High
Morphine 1 93.72 High High
tolerance 1 93.36 High High
Central nervous system 11 89.28 High High
Disease Link Frequency Relevance Heat
Injury 10 95.36 Very High Very High Very High
Pain 3 95.36 Very High Very High Very High
Nociception 1 95.00 High High
Hypersensitivity 1 94.56 High High
Generalized Anxiety Disorder 3 90.72 High High
Targeted Disruption 2 87.44 High High
Spinal Cord Injury 12 84.40 Quite High
Toxicity 1 60.84 Quite High
Neuropathic Pain 1 50.72 Quite High
INFLAMMATION 1 47.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results support these findings, where GFAP immunoreactivity was temporally associated with that of FGF-2 especially in SC1.
Gene_expression (especially) of SC1
1) Confidence 0.28 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2990542 Disease Relevance 0.08 Pain Relevance 0.12
Design and evaluation of small interfering RNAs that target expression of the N-methyl-D-aspartate receptor NR1 subunit gene in the spinal cord dorsal horn.
Gene_expression (expression) of spinal cord dorsal horn in spinal cord dorsal horn associated with nmda receptor, dorsal horn and spinal cord
2) Confidence 0.15 Published 2007 Journal J. Pharmacol. Exp. Ther. Section Title Doc Link 17551091 Disease Relevance 0.40 Pain Relevance 0.65
To gain insight into the cellular mechanism of 5-HT(3) receptors, we examined their expression in GABAergic and enkephalinergic (ENKergic) neurons in the spinal dorsal horn (SDH) using single-cell reverse transcription-polymerase chain reaction (RT-PCR).
Spec (examined) Gene_expression (expression) of spinal dorsal horn in neurons associated with spinal dorsal horn and gabaergic
3) Confidence 0.05 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18586398 Disease Relevance 0.43 Pain Relevance 0.40

General Comments

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