INT144533

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Context Info
Confidence 0.39
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 8
Disease Relevance 5.12
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gem) plasma membrane (Gem) GTPase activity (Gem)
Anatomy Link Frequency
brain 1
T-cell 1
Gem (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 100.00 Very High Very High Very High
Inflammation 36 90.16 High High
Pain 1 86.60 High High
Central nervous system 15 69.28 Quite High
agonist 11 44.04 Quite Low
chemokine 3 35.32 Quite Low
anesthesia 10 29.92 Quite Low
isoflurane 30 28.96 Quite Low
Thoracotomy 1 19.00 Low Low
Versed 1 8.36 Low Low
Disease Link Frequency Relevance Heat
Infection 51 97.24 Very High Very High Very High
Immunization 370 95.04 Very High Very High Very High
Apoptosis 60 93.52 High High
INFLAMMATION 39 90.16 High High
Non-small-cell Lung Cancer 16 89.64 High High
Sprains And Strains 21 87.76 High High
Fatigue 1 87.08 High High
Influenza Virus Infection 350 86.80 High High
Pain 1 86.60 High High
Lung Cancer 10 86.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, Gem expression localized over cells lining the meninges, while Cd83 and Tnfsf9 transcripts were distributed across parenchymal elements of the brain.
Gene_expression (expression) of Gem in brain
1) Confidence 0.39 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819560 Disease Relevance 0.08 Pain Relevance 0.03
One unit of GEM particles was defined as approximately 2.5?
Gene_expression (particles) of GEM
2) Confidence 0.35 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 0.98 Pain Relevance 0
After acid and heat treatment, the GEM particles were pelleted and washed three times in phosphate buffered saline (PBS; Dulbecco¬ís phosphate buffered saline without CaCl2 and MgCl2) and finally resuspended in PBS and stored at ?
Gene_expression (particles) of GEM
3) Confidence 0.35 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 1.09 Pain Relevance 0
GEM particles can be produced in large quantities under sterile conditions and can be stored at ambient temperature for long time (29).
Gene_expression (produced) of GEM
4) Confidence 0.31 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 0.62 Pain Relevance 0
During the production of GEM particles, L. lactis bacteria are treated with acid, which results in loss of genetic material.
Gene_expression (production) of GEM
5) Confidence 0.31 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 0.45 Pain Relevance 0
Moreover, the GEM particles are produced from a bacterium which is used in the production of dairy products and is considered a GRAS organism.
Gene_expression (produced) of GEM
6) Confidence 0.31 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 0.59 Pain Relevance 0
When GEM and PB were combined, either in high dosage (10 ?
Gene_expression (combined) of GEM
7) Confidence 0.27 Published 2006 Journal J Carcinog Section Body Doc Link PMC1665446 Disease Relevance 0.96 Pain Relevance 0
Blood samples were analysed for leukocyte subset cell counts, in vitro T-cell mitogen-stimulated cytokine production (IL-2, IL-4, IL-5, IL-6, IL-10, TNF-alpha and IFN-gamma) and in vitro monocyte cytokine release (IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha) in response to increasing concentrations of LPS.
Gene_expression (production) of T-cell mitogen-stimulated cytokine in T-cell associated with cytokine
8) Confidence 0.10 Published 2007 Journal Brain Behav. Immun. Section Abstract Doc Link 17553664 Disease Relevance 0.35 Pain Relevance 0.36

General Comments

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