INT144559

Context Info Confidence 0.45 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.88 Pain Relevance 1.60

Anatomy Mention Frequency spinal nerve 2

Pain Term Frequency Confidence Heat Brush evoked pain 2 98.68 Hyperalgesia 3 96.96 Spinal nerve ligature 8 96.52 allodynia 3 96.20 bradykinin 4 92.72 antagonist 1 89.36 agonist 2 83.20 Neuropathic pain 1 52.24 neuralgia 1 25.00

Disease Term Frequency Confidence Heat Neuropathic Pain 7 98.68 Hyperalgesia 3 96.96 Nociception 2 75.00 Injury 1 60.08 Nervous System Injury 1 51.24

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Western blot analysis revealed enhanced expression of kinin B(1) and B(2) receptor protein in ipsilateral L4-L6 spinal nerve and hind paw skin samples collected on Day 12 after SNL surgery.

Positive_regulation (enhanced) of Gene_expression (expression) of B(2) receptor protein in spinal nerve associated with spinal nerve ligature

1) Confidence 0.45 Published 2007 Journal Neuropharmacology Section Abstract Doc Link 17555775 Disease Relevance 0.88 Pain Relevance 1.60

General Comments

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