INT144611

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.51
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (THY1) endoplasmic reticulum (THY1) plasma membrane (THY1)
enzyme binding (THY1) cytoskeleton organization (THY1)
Anatomy Link Frequency
dendrites 1
ganglion cell 1
THY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Eae 12 99.68 Very High Very High Very High
rheumatoid arthritis 16 94.72 High High
Inflammation 10 64.56 Quite High
cINOD 2 60.88 Quite High
Arthritis 28 58.44 Quite High
Analgesic 1 25.00 Low Low
Spinal cord 3 6.00 Low Low
Hippocampus 8 5.00 Very Low Very Low Very Low
cerebral cortex 4 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 100.00 Very High Very High Very High
Targeted Disruption 46 99.06 Very High Very High Very High
Disease 90 96.08 Very High Very High Very High
Rheumatoid Arthritis 16 94.72 High High
Apoptosis 2 93.08 High High
INFLAMMATION 8 64.56 Quite High
Arthritis 29 58.44 Quite High
Stress 3 57.92 Quite High
Retinal Diseases 2 55.52 Quite High
Age-related Macular Degeneration 2 52.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unexpectedly, the expression of CD34 was present in the majority of cultures, albeit that the signal was not as strong as for the markers CD73, CD105, and CD90.
Neg (not) Regulation (strong) of CD90
1) Confidence 0.16 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875643 Disease Relevance 0.35 Pain Relevance 0.17
This was supported by RT-PCR data where rhodopsin (photoreceptor specific) mRNA was reduced while Thy-1 and NF-L (ganglion cell specific) mRNAs were unaffected.
Neg (unaffected) Regulation (unaffected) of Thy-1 in ganglion cell associated with ganglion cysts
2) Confidence 0.15 Published 2007 Journal Brain Res. Bull. Section Abstract Doc Link 17562394 Disease Relevance 0.50 Pain Relevance 0
The first transgenic mouse which expressed the longest tau isoform under control of the human Thy-1 promoter showed tau phosphorylation at sites which are usually found to be modified in PHFs and presented localization of human tau in neuronal soma, axons, and dendrites.
Regulation (control) of Thy-1 promoter in dendrites associated with targeted disruption and eae
3) Confidence 0.00 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915753 Disease Relevance 0.65 Pain Relevance 0.17

General Comments

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