INT144689

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Context Info
Confidence 0.53
First Reported 2003
Last Reported 2010
Negated 4
Speculated 2
Reported most in Body
Documents 49
Total Number 52
Disease Relevance 25.91
Pain Relevance 9.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
arm 2
plasma 1
liver 1
brainstem 1
Body 1
RCT (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 7 100.00 Very High Very High Very High
Percutaneous transluminal coronary angioplasty 4 99.96 Very High Very High Very High
Inflammation 67 99.76 Very High Very High Very High
Acupuncture 267 99.40 Very High Very High Very High
backache 134 99.40 Very High Very High Very High
agonist 80 99.40 Very High Very High Very High
Pain 560 99.00 Very High Very High Very High
complementary and alternative medicine 25 98.52 Very High Very High Very High
cINOD 42 98.40 Very High Very High Very High
pregabalin 18 98.40 Very High Very High Very High
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 1188 100.00 Very High Very High Very High
Disease 243 100.00 Very High Very High Very High
INFLAMMATION 79 99.76 Very High Very High Very High
Pneumonia 51 99.60 Very High Very High Very High
Low Back Pain 183 99.40 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 85 99.38 Very High Very High Very High
Clinical Trials And Case Reports 16 99.38 Very High Very High Very High
Cancer 62 99.36 Very High Very High Very High
Shoulder Impingement Syndrome 52 99.36 Very High Very High Very High
Scoliosis 35 99.32 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND: Cognitive behaviour therapy (CBT) has been shown to reduce psychological morbidity in people with cancer, but no randomized controlled trial (RCT) exists in palliative care.
Neg (no) Regulation (controlled) of RCT associated with cognitive disorder, cancer and palliative
1) Confidence 0.53 Published 2009 Journal Psychol Med Section Abstract Doc Link 18761755 Disease Relevance 0.42 Pain Relevance 0.14
No randomized controlled trial (RCT) on bracing for IS can be found in the Cochrane library or in PubMed.
Neg (No) Regulation (controlled) of RCT associated with scoliosis
2) Confidence 0.42 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2386134 Disease Relevance 0.36 Pain Relevance 0
STUDY DESIGN: Exploratory subgroup analysis in a randomized controlled trial (RCT).
Regulation (controlled) of RCT
3) Confidence 0.39 Published 2009 Journal Spine Section Abstract Doc Link 19412140 Disease Relevance 0.07 Pain Relevance 0.07
One randomized controlled trial (RCT) and 11 uncontrolled prospective studies provided data on efficacy; three additional studies assessed safety.
Regulation (controlled) of RCT
4) Confidence 0.39 Published 2008 Journal Clin. Rheumatol. Section Abstract Doc Link 17570009 Disease Relevance 0.54 Pain Relevance 0.45
In 2003/2007 a randomised controlled trial (RCT) was undertaken into the efficacy of aromatherapy in reducing levels of anxiety amongst palliative care patients.
Regulation (controlled) of RCT associated with anxiety disorder and palliative
5) Confidence 0.39 Published 2008 Journal Complementary therapies in clinical practice Section Abstract Doc Link 18640632 Disease Relevance 0.10 Pain Relevance 0.10
RCT randomized controlled trial
Regulation (controlled) of RCT
6) Confidence 0.33 Published 2003 Journal BMC Surg Section Body Doc Link PMC293467 Disease Relevance 0.08 Pain Relevance 0
A novel approach of the FINALE programme is that the interventions, i.e. 3 randomized controlled trials (RCT) and 1 exploratory case-control study are tailored to the physical work demands, physical capacities and health profile of workers in each job-group.
Regulation (controlled) of RCT
7) Confidence 0.30 Published 2010 Journal BMC Public Health Section Abstract Doc Link PMC2841104 Disease Relevance 0.13 Pain Relevance 0
Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development

The concept of 'equipoise', or the 'uncertainty principle', has been represented as a central ethical principle, and holds that a subject may be enrolled in a randomized controlled trial (RCT) only if there is true uncertainty about which of the trial arms is most likely to benefit the patient.

Regulation (controlled) of RCT in arms
8) Confidence 0.26 Published 2004 Journal Arthritis Res Ther Section Title Doc Link PMC416446 Disease Relevance 0 Pain Relevance 0
VERTOS, the first randomized controlled trial (RCT) with a limited group of 34 patients reports only on short-term results [16].
Regulation (controlled) of RCT
9) Confidence 0.23 Published 2007 Journal Trials Section Body Doc Link PMC2169262 Disease Relevance 1.01 Pain Relevance 0.58
The study is designed as a randomised controlled trial (RCT) with an economic evaluation.
Regulation (controlled) of RCT
10) Confidence 0.23 Published 2007 Journal BMC Geriatr Section Abstract Doc Link PMC1933430 Disease Relevance 0.08 Pain Relevance 0
Results from case series and a small-sample randomized controlled trial (RCT) suggest improved function and less pain after primary hemiarthroplasty (HA); however these studies had some limitations and a RCT is needed.
Regulation (controlled) of RCT associated with pain
11) Confidence 0.23 Published 2010 Journal BMC Musculoskelet Disord Section Abstract Doc Link 20500849 Disease Relevance 0.52 Pain Relevance 0.25
Indeed, the only randomized controlled trial (RCT)—the Women's Health Initiative (WHI) study—failed to support this contention overall.
Regulation (controlled) of RCT
12) Confidence 0.22 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1872041 Disease Relevance 0.84 Pain Relevance 0.14
The results of this study demonstrate that voluntary exercise in mice increases the efflux capacity of plasma despite a tendency towards decreased plasma HDL cholesterol levels, but does not alter macrophage-to-feces RCT.
Neg (not) Regulation (alter) of RCT in plasma associated with disorder of lipid metabolism
13) Confidence 0.21 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2903598 Disease Relevance 0.29 Pain Relevance 0.13
RCT randomised controlled trial
Regulation (controlled) of RCT
14) Confidence 0.14 Published 2007 Journal BMC Surg Section Body Doc Link PMC2198905 Disease Relevance 0.22 Pain Relevance 0.22
If it is enough to document effects as different from the natural course of the disease, a waiting list controlled RCT is an option.
Regulation (controlled) of RCT associated with disease
15) Confidence 0.12 Published 2006 Journal BMC Med Res Methodol Section Body Doc Link PMC1540434 Disease Relevance 0.16 Pain Relevance 0
RCT – randomised controlled trial



Regulation (controlled) of RCT
16) Confidence 0.12 Published 2007 Journal Aust New Zealand Health Policy Section Body Doc Link PMC1810306 Disease Relevance 0.10 Pain Relevance 0.15
RCT Randomized control trial

Competing interests

Regulation (control) of RCT
17) Confidence 0.12 Published 2007 Journal Implement Sci Section Body Doc Link PMC1899518 Disease Relevance 1.19 Pain Relevance 0.10
Clinical experience from numerous case reports and series, retrospective and prospective open label cohort studies, and randomized controlled trials (RCT) has grown over the past 10 years.
Regulation (controlled) of RCT
18) Confidence 0.12 Published 2009 Journal J Neural Transm Section Abstract Doc Link 19142573 Disease Relevance 0.66 Pain Relevance 0.05
Several other properties of HDL beyond its involvement in the RCT pathway exert additional anti-atherogenic influence.16,17 HDL has been shown to directly stimulate tissue plasminogen activator (tPA) and inhibit the expression of plasminogen activator inhibitor-1 (PAI-1).
Regulation (involvement) of RCT associated with disorder of lipid metabolism
19) Confidence 0.10 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 1.11 Pain Relevance 0.06
The mechanisms, by which exercise and reduced weight increase HDL-C likely involves enchanced lipoprotein lipase (LL) activity, increased RCT, and increased levels of pre-?
Regulation (involves) of RCT associated with disorder of lipid metabolism
20) Confidence 0.10 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.02 Pain Relevance 0.04

General Comments

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