INT144761

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (INSR, Insr) endosome (INSR, Insr) plasma membrane (INSR, Insr)
nucleus (INSR, Insr) carbohydrate metabolic process (INSR)
INSR (Homo sapiens)
Insr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 50.00 Quite Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 2 50.00 Quite Low
Disease 1 5.00 Very Low Very Low Very Low
Weight Loss 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Vitamin Deficiency 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: The regulatory mechanisms of PP-mediated hepatic IR expression and combined IR and GLUT2 endocytosis after insulin binding are defective in chronic pancreatitis and contribute to the apancreatic diabetes, which characterizes this disease.


IR Binding (binding) of insulin
1) Confidence 0.05 Published 2007 Journal Pancreas Section Body Doc Link 17575539 Disease Relevance 0 Pain Relevance 0

General Comments

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