INT144782

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.67
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (LY6E)
Anatomy Link Frequency
spinal 1
Stem 1
LY6E (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 11 100.00 Very High Very High Very High
Calcium channel 1 100.00 Very High Very High Very High
hyperexcitability 1 92.80 High High
depression 1 86.48 High High
cytokine 4 83.76 Quite High
headache 2 73.68 Quite High
Inflammation 1 5.44 Low Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 8 100.00 Very High Very High Very High
Ataxia 4 100.00 Very High Very High Very High
Cerebellar Diseases 1 96.68 Very High Very High Very High
Migraine With Aura 2 95.24 Very High Very High Very High
Migraine Without Aura 1 88.68 High High
Depression 1 86.48 High High
Migraine Disorders 2 85.88 High High
Congenital Anomalies 2 81.60 Quite High
Injury 8 12.40 Low Low
INFLAMMATION 2 5.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Assessment of cells bearing this phenotype was performed at similar timepoints to CD34/C133 expression pre- and post-Stem-Kine administration.
Gene_expression (expression) of Stem-Kine in Stem
1) Confidence 0.01 Published 2010 Journal J Transl Med Section Body Doc Link PMC2862021 Disease Relevance 0 Pain Relevance 0.04
Purkinje cells express calcium channels that are related to the pathophysiology of both inherited forms of migraine and primary ataxias, mostly spinal cerebellar ataxia type 6 (SCA-6) and episodic ataxia type 2 (EA-2).
Gene_expression (express) of SCA-6 in spinal associated with ataxia, migraine and calcium channel
2) Confidence 0.01 Published 2007 Journal Headache Section Abstract Doc Link 17578530 Disease Relevance 1.67 Pain Relevance 1.08

General Comments

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