INT144790

Context Info Confidence 0.53 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0.40

transport (Hcn2) plasma membrane (Hcn2) transmembrane transport (Hcn2)

Hcn2 (Mus musculus)

Pain Link Frequency Relevance Heat hCN2 6 100.00 HCN1 2 96.20 Angina 1 60.60

Disease Link Frequency Relevance Heat Cv General 3 Under Development 1 60.60

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Mutation of Ala425 and Ile432 also attenuated the block of HCN2 by the more potent blocker cilobradine.

Negative_regulation (attenuated) of Negative_regulation (block) of HCN2 associated with hcn2

1) Confidence 0.53 Published 2007 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 17578902 Disease Relevance 0.06 Pain Relevance 0.40

General Comments

This test has worked.