INT144920

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Context Info
Confidence 0.65
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TGFBR1) aging (TGFBR1) cell motility (TGFBR1)
plasma membrane (TGFBR1) embryo development (TGFBR1)
Anatomy Link Frequency
nucleus pulposus 4
TGFBR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
backache 2 28.08 Quite Low
Disease Link Frequency Relevance Heat
Intervertebral Disk Degeneration 2 5.00 Very Low Very Low Very Low
Low Back Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have reported that the capacity of human intervertebral nucleus pulposus cell line to synthesize proteoglycan (PG) was increased by exposure to LIPUS, and postulated that one of the mechanisms underlying this response was an increase in expression of the transforming growth factor-beta type I receptor gene (TGFbetaR1).
Positive_regulation (increase) of Gene_expression (expression) of TGFbetaR1 in nucleus pulposus
1) Confidence 0.65 Published 2007 Journal J. Orthop. Res. Section Abstract Doc Link 17593536 Disease Relevance 0 Pain Relevance 0
We have reported that the capacity of human intervertebral nucleus pulposus cell line to synthesize proteoglycan (PG) was increased by exposure to LIPUS, and postulated that one of the mechanisms underlying this response was an increase in expression of the transforming growth factor-beta type I receptor gene (TGFbetaR1).
Positive_regulation (increase) of Gene_expression (expression) of transforming growth factor-beta type I receptor gene in nucleus pulposus
2) Confidence 0.41 Published 2007 Journal J. Orthop. Res. Section Abstract Doc Link 17593536 Disease Relevance 0 Pain Relevance 0

General Comments

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