INT144981

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.66
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (F2R) Golgi apparatus (F2R) plasma membrane (F2R)
signal transducer activity (F2R)
Anatomy Link Frequency
endothelial cells 1
F2R (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 2 98.00 Very High Very High Very High
Pain 120 95.92 Very High Very High Very High
c fibre 73 88.04 High High
nociceptor 22 5.00 Very Low Very Low Very Low
metalloproteinase 11 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
qutenza 8 5.00 Very Low Very Low Very Low
Pain threshold 6 5.00 Very Low Very Low Very Low
COX-2 inhibitor 6 5.00 Very Low Very Low Very Low
unmyelinated 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myalgia 8 99.60 Very High Very High Very High
Pain 110 95.92 Very High Very High Very High
Nociception 27 94.32 High High
Metastasis 2 87.48 High High
Cancer 45 86.24 High High
Hypoxia 2 85.40 High High
Reprotox - General 1 26 79.32 Quite High
Adenocarcinoma 1 55.12 Quite High
Ductal Carcinoma 2 37.20 Quite Low
Increased Venous Pressure Under Development 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SNPs in the HTR3B and HTR7 genes, rs2276307 and rs1935349, respectively, were significantly associated with the myalgia score.
HTR Binding (associated) of associated with myalgia
1) Confidence 0.36 Published 2007 Journal Muscle Nerve Section Abstract Doc Link 17600820 Disease Relevance 0.94 Pain Relevance 0.26
A number of markers expressed by the MDA-MB-231 cells, including thrombin receptor, TIE-2, CD31, VEGF, and bc-48, have been shown to be associated with endothelial cells [30-34].
thrombin receptor Binding (associated) of in endothelial cells
2) Confidence 0.05 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1797025 Disease Relevance 0.72 Pain Relevance 0
for each subgroup; (10) checking the linearity of the function tR?
tR Binding (linearity) of
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2859063 Disease Relevance 0 Pain Relevance 0.09

General Comments

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