INT145009

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.18
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (VDR) signal transduction (VDR) cell morphogenesis (VDR)
nucleus (VDR) DNA binding (VDR)
Anatomy Link Frequency
muscle 2
VDR (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 100.00 Very High Very High Very High
carbamazepine 17 98.08 Very High Very High Very High
antiepileptic Drug 1 50.00 Quite Low
Lamotrigine 1 6.64 Low Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
antidepressant 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 35 100.00 Very High Very High Very High
Rickets 7 100.00 Very High Very High Very High
Disease 2 100.00 Very High Very High Very High
Muscle Weakness 1 99.96 Very High Very High Very High
Hypophosphatemia 3 99.44 Very High Very High Very High
Hypocalcemia 8 98.60 Very High Very High Very High
Congenital Anomalies 2 85.44 High High
Frailty 2 77.88 Quite High
Hypercalcemia 16 49.36 Quite Low
Exanthema 1 47.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vitamin D deficiency causes osteopenia, precipitates and exacerbates osteoporosis, causes a painful disease, osteomalacia, and increases muscle weakness, which worsens the risk of falls and fractures.
Positive_regulation (increases) of Negative_regulation (deficiency) of Vitamin D in muscle associated with pain, rickets, muscle weakness, osteoporosis and disease
1) Confidence 0.41 Published 2007 Journal Maturitas Section Abstract Doc Link 17604580 Disease Relevance 0.56 Pain Relevance 0.10
These enzyme inducing AEDs may increase catabolism of vitamin D resulting in hypophosphatemia and hypocalcemia.
Spec (may) Positive_regulation (increase) of Negative_regulation (catabolism) of vitamin D associated with hypocalcemia and hypophosphatemia
2) Confidence 0.19 Published 2006 Journal Nutr Metab (Lond) Section Body Doc Link PMC1586194 Disease Relevance 0.62 Pain Relevance 0.15

General Comments

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