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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.83

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pigmentation (ASIP) signal transduction (ASIP) generation of precursor metabolites and energy (ASIP)
extracellular space (ASIP) extracellular region (ASIP) cell-cell signaling (ASIP)
ASIP (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 11 98.16 Very High Very High Very High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 3 species (2 lemurs and the howler monkey), we report the novel finding that binding and inhibition of MC1R by agouti signaling protein (ASIP) can occur when MSH binding has been lost, thus enabling continuing regulation of the melanin type via ASIP expression.
Regulation (continuing) of Gene_expression (expression) of ASIP associated with melanocortin 1 receptor
1) Confidence 0.27 Published 2007 Journal Mol. Biol. Evol. Section Abstract Doc Link 17609536 Disease Relevance 0 Pain Relevance 0.83

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