INT145098

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Context Info
Confidence 0.66
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.33
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NGF, BDNF) endosome (NGF) signal transduction (NGF)
extracellular space (NGF) cytoplasmic membrane-bounded vesicle (BDNF)
NGF (Homo sapiens)
BDNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 7 100.00 Very High Very High Very High
Fibrositis 8 97.24 Very High Very High Very High
Migraine 6 96.88 Very High Very High Very High
Pain 4 95.72 Very High Very High Very High
Glutamate 3 95.16 Very High Very High Very High
central sensitization 1 76.16 Quite High
Lasting pain 3 73.76 Quite High
headache 1 69.24 Quite High
Disease Link Frequency Relevance Heat
Fibromyalgia 6 97.24 Very High Very High Very High
Headache 6 96.88 Very High Very High Very High
Pain 5 73.76 Quite High
Headache Disorders 1 69.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest the possibility of a NGF-mediated up-regulation of BDNF involved in the pathophysiological events underlying long-term neuroplastic changes in persistent chronic painful conditions, such as CM and fibromyalgia.
NGF Positive_regulation (up-regulation) of BDNF associated with pain, nerve growth factor, migraine and fibrositis
1) Confidence 0.66 Published 2007 Journal J Pain Section Abstract Doc Link 17611164 Disease Relevance 1.33 Pain Relevance 1.67

General Comments

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