INT1451

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Context Info
Confidence 0.06
First Reported 1978
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.67
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CPN1) extracellular space (CPN1) extracellular region (CPN1)
Anatomy Link Frequency
neuron 1
CPN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 14 100.00 Very High Very High Very High
cINOD 2 99.36 Very High Very High Very High
Angina 1 84.72 Quite High
bradykinin 6 64.32 Quite High
addiction 26 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 99.16 Very High Very High Very High
Myocardial Infarction 10 97.58 Very High Very High Very High
Infarction 1 90.40 High High
Angina 1 84.72 Quite High
Nociception 2 83.84 Quite High
Blister 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Worthy of note is the finding that in two acute myocardial infarction patients presenting MB2/MB1 ratios lower than the cutoff value (1.5) throughout the period of observation, the baseline values for carboxypeptidase N were higher than in other patients studied.
Regulation (values) of carboxypeptidase N associated with myocardial infarction
1) Confidence 0.06 Published 1997 Journal Eur J Clin Chem Clin Biochem Section Abstract Doc Link 9166972 Disease Relevance 0.56 Pain Relevance 0.08
Effect of carboxypeptidase N, aprotinin and anti-inflammatory drugs of pyrazolidine type on experimental inflammations in rats.
Regulation (Effect) of carboxypeptidase N associated with inflammation and cinod
2) Confidence 0.04 Published 1978 Journal Pharmacology Section Title Doc Link 201946 Disease Relevance 0.58 Pain Relevance 0.48
Inflammation was induced by application of kaolin into the hind paws of rats and its development under the influence of carboxypeptidase N and aprotinin (Antilysin) was followed and compared with the effect of the phenylbutazone type of drugs.
Regulation (influence) of carboxypeptidase N associated with inflammation
3) Confidence 0.03 Published 1978 Journal Pharmacology Section Abstract Doc Link 201946 Disease Relevance 0.53 Pain Relevance 0.26
Our data permitted comparison of CDN/CPN and CDT/CPT for only a single neuron (the results were identical), so any difference is purely speculative.
Regulation (permitted) of CPN in neuron
4) Confidence 0.01 Published 2008 Journal Journal of Neurophysiology Section Body Doc Link PMC2576218 Disease Relevance 0 Pain Relevance 0

General Comments

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