INT145121

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) nuclear chromosome (Msh3) plasma membrane (Oprm1)
nucleus (Msh3) enzyme binding (Msh3) DNA binding (Msh3)
Anatomy Link Frequency
neurons 1
Msh3 (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 5 100.00 Very High Very High Very High
gABA 7 99.00 Very High Very High Very High
Glutamate 2 98.34 Very High Very High Very High
antagonist 1 90.88 High High
Action potential 1 83.48 Quite High
agonist 2 68.56 Quite High
GABAergic 1 63.88 Quite High
Opioid 1 62.68 Quite High
Disease Link Frequency Relevance Heat
Infection 1 92.00 High High
Targeted Disruption 1 57.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glutamate photolysis stimulation of intact NTS projections evoked IPSCs in DMV neurons, and EM-1 reduced the evoked response, most likely by activation of MOR on the soma of premotor GABA neurons in NTS.
EM-1 Positive_regulation (activation) of MOR in neurons associated with gaba, glutamate and opioid receptor
1) Confidence 0.06 Published 2007 Journal J. Neurophysiol. Section Abstract Doc Link 17615134 Disease Relevance 0.15 Pain Relevance 0.72

General Comments

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