INT145142

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.54
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RPL5) structural constituent of ribosome (RPL5) ribosome (RPL5)
nucleolus (RPL5) RNA binding (RPL5) nucleus (RPL5)
Anatomy Link Frequency
cornea 1
RPL5 (Homo sapiens)
RPL5 - V60L (1)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 9 91.08 High High
Inflammation 20 89.04 High High
metalloproteinase 5 87.80 High High
cytokine 3 71.76 Quite High
ketamine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 13 98.64 Very High Very High Very High
Aspergillus Infection 3 95.40 Very High Very High Very High
Candida Infection 3 94.40 High High
Infection 3 93.52 High High
Corneal Neovascularization 41 93.04 High High
Chemical Burns 5 92.64 High High
Necrosis 2 90.52 High High
Cancer 3 90.16 High High
INFLAMMATION 21 89.04 High High
Corneal Disease 10 88.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of 8 HKGs (glyceraldehyde-3-phosphate dehydrogenase [GAPDH], beta-actin [ACTB], lactate dehydrogenase A [LDHA], ribosomal protein L5 [RPL5], ubiquitin C [UBC], peptidylprolyl isomerase A [PPIA], TATA-box binding protein [TBP1], and hypoxanthine guanine phosphoribosyl transferase [HPRT1]) in the cornea were measured at various time points by microarray hybridization or qRT–PCR and the data analyzed using geNorm and NormFinder.


Spec (analyzed) Gene_expression (Expression) of RPL5 in cornea
1) Confidence 0.12 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2893048 Disease Relevance 0.84 Pain Relevance 0
The expression level of RPL5 was similar in each group.
Gene_expression (expression) of RPL5
2) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2751803 Disease Relevance 0.61 Pain Relevance 0.21
In vitro expression studies revealed that variant receptors with reduced cell surface expression, including V60L, D84E, R151C, I155T, R160W and R163Q, showed a corresponding impairment in cAMP coupling.
Gene_expression (expression) of V60L (V60L)
3) Confidence 0.00 Published 2007 Journal Hum. Mol. Genet. Section Abstract Doc Link 17616515 Disease Relevance 0.09 Pain Relevance 0.41

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox