INT145147

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.91
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TP63) nucleoplasm (TP63) anatomical structure formation involved in morphogenesis (TP63)
Golgi apparatus (TP63) nucleolus (TP63) nucleus (TP63)
TP63 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 1 97.44 Very High Very High Very High
imagery 11 80.88 Quite High
Central nervous system 1 62.72 Quite High
endometriosis 8 50.00 Quite Low
Dismenorea 2 50.00 Quite Low
headache 5 28.28 Quite Low
palliative 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leiomyosarcoma 13 100.00 Very High Very High Very High
Skin Cancer 20 99.76 Very High Very High Very High
Sarcoma 49 97.24 Very High Very High Very High
Cancer 186 92.20 High High
Metastasis 40 89.44 High High
Disease 21 87.80 High High
Craniopharyngioma 10 75.32 Quite High
Liposarcoma 5 51.40 Quite High
Endometriosis 12 50.00 Quite Low
Malignant Fibrous Histiocytoma 12 43.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nevertheless, it remains unclear whether the lack of p63 expression in some lesions is related to the extent of the disease, to its clinical behavior, or to exacerbation of the accompanying symptoms.


Spec (whether) Negative_regulation (lack) of Gene_expression (expression) of p63
1) Confidence 0.42 Published 2007 Journal Arch. Pathol. Lab. Med. Section Body Doc Link 17616998 Disease Relevance 0 Pain Relevance 0
Immunohistochemistry was used to evaluate p63 expression.
Negative_regulation (evaluate) of Gene_expression (expression) of p63
2) Confidence 0.42 Published 2007 Journal Arch. Pathol. Lab. Med. Section Body Doc Link 17616998 Disease Relevance 0 Pain Relevance 0
However, in two poorly differentiated OSCC a complete absence of p63 expression in the sarcomatoid component was found indicating a more complete transition towards the mesenchymal phenotype.
Negative_regulation (absence) of Gene_expression (expression) of p63 associated with skin cancer
3) Confidence 0.18 Published 2010 Journal BMC Clin Pathol Section Body Doc Link PMC2829523 Disease Relevance 0.61 Pain Relevance 0
Immunohistochemistry revealed expression of pancytokeratin, high-molecular weight cytokeratin and p63.
Negative_regulation (revealed) of Gene_expression (expression) of p63
4) Confidence 0.06 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2330022 Disease Relevance 0.67 Pain Relevance 0.15
Perhaps, LMS of the prostate may represent a more
Negative_regulation (more) of Gene_expression (represent) of LMS associated with leiomyosarcoma
5) Confidence 0.03 Published 2006 Journal Sarcoma Section Body Doc Link PMC1510952 Disease Relevance 1.64 Pain Relevance 0

General Comments

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