INT145150

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (EGFR, JUN) nucleoplasm (JUN) nuclear chromosome (JUN)
aging (JUN) DNA binding (JUN) extracellular space (EGFR)
EGFR (Homo sapiens)
JUN (Homo sapiens)
Pain Link Frequency Relevance Heat
peptic ulcer disease 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alagille Syndrome 2 57.44 Quite High
Stomach Cancer 6 50.00 Quite Low
Gastritis 6 50.00 Quite Low
Cancer 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Ulcers 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of c-Jun and c-Fos to the EGFR promoter region -1,062/-900 was induced eight- and six fold, respectively, using ChIP assay.
Positive_regulation (induced) of EGFR promoter Binding (Binding) of c-Jun
1) Confidence 0.24 Published 2007 Journal Am. J. Gastroenterol. Section Body Doc Link 17617207 Disease Relevance 0.05 Pain Relevance 0
We found that AP-1 activity was induced by H. pylori in gastric cells, while electrophoretic mobility shift assays confirmed that binding of AP-1 to the EGFR promoter site was increased following H. pylori treatment.
Positive_regulation (increased) of EGFR promoter site Binding (binding) of AP-1
2) Confidence 0.24 Published 2007 Journal Am. J. Gastroenterol. Section Body Doc Link 17617207 Disease Relevance 0.06 Pain Relevance 0

General Comments

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