INT145156

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Context Info
Confidence 0.24
First Reported 2006
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.31
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (EGFR) cell morphogenesis (EGFR) Golgi apparatus (EGFR)
endoplasmic reticulum (EGFR) intracellular (EGFR) enzyme binding (EGFR)
Anatomy Link Frequency
AGS 2
EGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 5 57.84 Quite High
Inflammation 19 5.00 Very Low Very Low Very Low
Crohn's disease 14 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
peptic ulcer disease 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 149 99.44 Very High Very High Very High
Disease 35 97.72 Very High Very High Very High
Lung Cancer 29 91.28 High High
Alagille Syndrome 1 90.00 High High
Adenocarcinoma 21 89.60 High High
Nicotine Addiction 16 71.20 Quite High
Salmonella Infection 5 56.04 Quite High
Stomach Cancer 13 50.00 Quite Low
Gastritis 3 50.00 Quite Low
Congenital Anomalies 4 46.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate the effects on EGFR regulation, AGS cells were transfected with a full-length and truncated EGFR luciferase (luc) reporter.
Spec (investigate) Regulation (effects) of Spec (investigate) Regulation (regulation) of EGFR in AGS
1) Confidence 0.24 Published 2007 Journal Am. J. Gastroenterol. Section Body Doc Link 17617207 Disease Relevance 0.09 Pain Relevance 0
Supervised clustering analysis based on EGFR gene mutations elucidated a subgroup including all EGFR gene mutated tumors, which showed significantly shorter disease-free survival
Regulation (elucidated) of Regulation (subgroup) of EGFR associated with cancer and disease
2) Confidence 0.22 Published 2006 Journal J Transl Med Section Body Doc Link PMC1479838 Disease Relevance 1.22 Pain Relevance 0.03

General Comments

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