INT145280

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 5.89
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
striatum 4
cortex 1
cerebellum 1
hb (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 21 97.96 Very High Very High Very High
fibrosis 207 97.28 Very High Very High Very High
Neurobehavioral 6 61.24 Quite High
addiction 1 51.36 Quite High
Central nervous system 9 48.80 Quite Low
Inflammation 19 43.32 Quite Low
Lasting pain 1 42.76 Quite Low
cytokine 9 11.00 Low Low
depression 9 6.64 Low Low
monoamine 39 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaemia 26 99.72 Very High Very High Very High
Idiopathic Pulmonary Fibrosis 207 97.28 Very High Very High Very High
Disease 54 96.52 Very High Very High Very High
Pulmonary Disease 192 94.72 High High
Targeted Disruption 330 90.04 High High
Congenital Anomalies 28 88.32 High High
Nicotine Addiction 27 84.44 Quite High
Apoptosis 1 83.28 Quite High
Injury 2 82.48 Quite High
Increased Venous Pressure Under Development 7 81.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HB (lox/lox) mice showed the same expression patterns for HB-EGF mRNA and protein in various regions of the brain (hippocampus, prefrontal cortex, cerebellum, and striatum) when compared with wild-type C57BL/6J mice (data not shown).
Regulation (patterns) of Gene_expression (expression) of HB-EGF in striatum associated with hippocampus
1) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759290 Disease Relevance 0.80 Pain Relevance 0.12
There is emerging evidence to suggest that the adverse effects of anemia are not only related to Hb levels but also to the low levels of EPO.
Regulation (related) of Gene_expression (levels) of Hb associated with anaemia
2) Confidence 0.23 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673829 Disease Relevance 1.10 Pain Relevance 0.03
The position of both "spot trains" in the 2-D gel and the theoretical molecular masses of Hb?
Regulation (position) of Gene_expression (masses) of Hb
3) Confidence 0.18 Published 2010 Journal Respir Res Section Body Doc Link PMC2949726 Disease Relevance 0.85 Pain Relevance 0.27
The results on the Hb complexes were very similar in the standard (Figure 2) and non-reducing Western blot (not shown) i.e. the presence of the Hb?
Regulation (results) of Gene_expression (complexes) of Hb
4) Confidence 0.18 Published 2010 Journal Respir Res Section Body Doc Link PMC2949726 Disease Relevance 0.80 Pain Relevance 0.19
but also for Hb?
Regulation (also) of Gene_expression (for) of Hb
5) Confidence 0.18 Published 2010 Journal Respir Res Section Body Doc Link PMC2949726 Disease Relevance 0.60 Pain Relevance 0.15
HB (lox/lox) mice showed the same expression patterns for HB-EGF mRNA and protein in various regions of the brain (hippocampus, prefrontal cortex, cerebellum, and striatum) when compared with wild-type C57BL/6J mice (data not shown).
Regulation (patterns) of in cerebellum Gene_expression (expression) of HB-EGF in striatum associated with hippocampus
6) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759290 Disease Relevance 0.80 Pain Relevance 0.12
HB (lox/lox) mice showed the same expression patterns for HB-EGF mRNA and protein in various regions of the brain (hippocampus, prefrontal cortex, cerebellum, and striatum) when compared with wild-type C57BL/6J mice (data not shown).
Regulation (patterns) of in cortex Gene_expression (expression) of HB-EGF in striatum associated with hippocampus
7) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2759290 Disease Relevance 0.80 Pain Relevance 0.12
Significant increase and decrease in RBC and WBC were recorded, respectively, but no changes in levels of PCV and Hb.
Neg (no) Regulation (changes) of Gene_expression (levels) of Hb
8) Confidence 0.08 Published 2007 Journal J Ethnopharmacol Section Abstract Doc Link 17628367 Disease Relevance 0.14 Pain Relevance 0

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