INT145457

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Clec7a)
Clec7a (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 8 79.84 Quite High
cytokine 10 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Renal Failure 2 98.24 Very High Very High Very High
Nephrotoxicity 1 75.00 Quite High
Hepatotoxicity 1 48.56 Quite Low
Suicidal Behaviour 1 42.20 Quite Low
Plasmodium Infection 17 5.00 Very Low Very Low Very Low
INFLAMMATION 14 5.00 Very Low Very Low Very Low
Infection 9 5.00 Very Low Very Low Very Low
Fever 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Parasitemia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Lyn/Syk activation finding raises the intriguing possibility that an as yet unidentified receptor or adaptor protein containing an ITAM or ITAM-like domain, such as Dectin-1, TREM family members, Siglec or DAP12 [26],[27], might be activated upon Hz stimulation to trigger the signaling cascade involved in inflammasome activation.
Positive_regulation (activated) of Dectin-1
1) Confidence 0.04 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
However, transient increase in NAG, NAG-B, alpha-GST, beta-Gr, GGT and beta2M enzymes was observed.
Positive_regulation (increase) of beta-Gr
2) Confidence 0.03 Published 2006 Journal Prz. Lek. Section Abstract Doc Link 17642144 Disease Relevance 0.17 Pain Relevance 0.34

General Comments

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