INT145621

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.06

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cytosol (PKLR) small molecule metabolic process (PKLR) endoplasmic reticulum (UGT2B7)
carbohydrate metabolic process (PKLR) lipid metabolic process (UGT2B7)
PKLR (Homo sapiens)
UGT2B7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 1 63.44 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Evaluation of 12 recombinant human UGT isozymes shows gemfibrozil glucuronidation activity in UGT1A1, UGT1A3, UGT1A9, UGT2B4, UGT2B7, and UGT2B17, with UGT2B7 showing the highest activity.
isozymes Binding (Evaluation) of UGT2B7
1) Confidence 0.02 Published 2007 Journal Drug Metab. Dispos. Section Abstract Doc Link 17670842 Disease Relevance 0 Pain Relevance 0.06

General Comments

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