INT145757

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.68
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tlr2) cytoplasm (Tlr2)
Anatomy Link Frequency
whiskers 2
Tlr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory marker 1 54.52 Quite High
cytokine 7 48.64 Quite Low
Inflammation 11 48.24 Quite Low
Inflammatory mediators 1 30.64 Quite Low
fifth nerve 3 5.00 Very Low Very Low Very Low
trigeminal ganglion 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 47 89.68 High High
Cold Sores 61 87.52 High High
Viral Meningitis 32 62.20 Quite High
Viral Infection 1 56.72 Quite High
INFLAMMATION 14 54.20 Quite High
Cv General 3 Under Development 1 52.24 Quite High
Herpes Simplex Virus 4 50.00 Quite Low
Pathologic Constriction 1 50.00 Quite Low
Arterial Occlusive Diseases 1 46.56 Quite Low
Infection 29 21.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, DA rats presented lower expression of Tlr2 in the whiskers area at 1–2 dpi (Figure 5A) and Tlr9 from 2 dpi (Figure 5D), correlating with a lower recruitment of phagocyting cells in this compartment (Figure 4C and 4M).
Negative_regulation (presented) of Gene_expression (expression) of Tlr2 in whiskers
1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.63 Pain Relevance 0.03
Systemic TLR2 and TLR4 response and expression decrease after PCI.
Negative_regulation (decrease) of Gene_expression (expression) of TLR2
2) Confidence 0.30 Published 2008 Journal Heart Section Body Doc Link 17686802 Disease Relevance 0.05 Pain Relevance 0

General Comments

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