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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.98
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tlr2) cytoplasm (Tlr2)
Anatomy Link Frequency
brain stem 2
lungs 2
Tlr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 87.40 High High
cytokine 27 69.12 Quite High
Inflammation 34 68.76 Quite High
Angina 5 50.00 Quite Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
fifth nerve 3 5.00 Very Low Very Low Very Low
trigeminal ganglion 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 1 98.40 Very High Very High Very High
Stable Angina Pectoris 4 92.88 High High
Arterial Occlusive Diseases 1 92.72 High High
Acute Coronary Syndrome 4 92.56 High High
INFLAMMATION 46 87.00 High High
Viral Infection 1 74.08 Quite High
Sprains And Strains 47 71.88 Quite High
Injury 1 65.56 Quite High
Pressure And Volume Under Development 2 55.44 Quite High
Lung Injury 13 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In DA rats increased expression of Tlr2 was observed in the trigeminal ganglia at 2 dpi and in the brain stem at 4 dpi, while the expression in PVG rats was unchanged.
Neg (unchanged) Regulation (unchanged) of Gene_expression (expression) of Tlr2 in brain stem
1) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.36 Pain Relevance 0.04
OBJECTIVE: To examine the effect of a percutaneous coronary intervention (PCI) on TLR2 and TLR4 response and expression.
Spec (examine) Regulation (effect) of Gene_expression (expression) of TLR2
2) Confidence 0.31 Published 2008 Journal Heart Section Body Doc Link 17686802 Disease Relevance 0.19 Pain Relevance 0
As shown in Figure 3, mechanically ventilated animals up-regulated TLR4 but not TLR2 protein levels in the lungs.
Neg (not) Regulation (regulated) of Neg (not) Gene_expression (levels) of TLR2 in lungs
3) Confidence 0.19 Published 2010 Journal Respir Res Section Body Doc Link PMC2841148 Disease Relevance 0.24 Pain Relevance 0.10
TLR2 and TLR4 expression levels in the PBMCs were significantly higher in the ACS group than in the SAP group.
Regulation (higher) of Gene_expression (expression) of TLR2
4) Confidence 0.14 Published 2009 Journal Circ. J. Section Body Doc Link 19556696 Disease Relevance 0.19 Pain Relevance 0

General Comments

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