INT145824

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Context Info
Confidence 0.48
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ngf) extracellular space (Ngf) extracellular region (Ngf)
nucleus (Fos) DNA binding (Fos) transcription factor binding (Fos)
Anatomy Link Frequency
spinal cord 2
Ngf (Mus musculus)
Fos (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 1 100.00 Very High Very High Very High
Spinal cord 1 99.68 Very High Very High Very High
Pain 12 97.92 Very High Very High Very High
Nerve growth factor 2 96.28 Very High Very High Very High
Morphine 1 92.08 High High
depression 1 80.60 Quite High
opiate 1 78.36 Quite High
cINOD 1 76.28 Quite High
Disease Link Frequency Relevance Heat
Pain 8 97.92 Very High Very High Very High
Osteoporotic Fractures 1 84.04 Quite High
Respiratory Failure 1 80.60 Quite High
Cognitive Disorder 1 79.04 Quite High
INFLAMMATION 1 76.04 Quite High
Malignant Neoplastic Disease 1 75.00 Quite High
Hyperalgesia 1 58.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with anti-NGF reduced c-Fos and dynorphin up-regulation in the spinal cord at day 2 post-fracture.
Negative_regulation (reduced) of NGF Positive_regulation (up-regulation) of c-Fos in spinal cord associated with dynorphin and spinal cord
1) Confidence 0.48 Published 2007 Journal Pain Section Abstract Doc Link 17693023 Disease Relevance 0.95 Pain Relevance 0.97

General Comments

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