INT145930

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.06
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2) aging (Bcl2) cell morphogenesis (Bcl2)
endoplasmic reticulum (Bcl2) intracellular (Bcl2) response to stress (Bcl2)
Anatomy Link Frequency
nucleus 2
hippocampus 2
ecs (Mus musculus)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 4 99.68 Very High Very High Very High
amygdala 10 98.60 Very High Very High Very High
fluoxetine 4 94.80 High High
antidepressant 8 91.92 High High
depression 2 78.20 Quite High
Disease Link Frequency Relevance Heat
Convulsion 8 100.00 Very High Very High Very High
Stress 12 81.64 Quite High
Depression 2 78.20 Quite High
Apoptosis 4 75.00 Quite High
Affective Disorder 2 66.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reboxetine, tranylcypromine, and ECS selectively increased Bcl-xl, but not Bcl-2 mRNA expression in the hippocampus.
ECS Neg (not) Positive_regulation (increased) of Gene_expression (expression) of Bcl-2 mRNA in hippocampus associated with convulsion and hippocampus
1) Confidence 0.01 Published 2008 Journal Neuropsychopharmacology Section Abstract Doc Link 17700647 Disease Relevance 1.04 Pain Relevance 0.67
Chemical ADT but not ECS, robustly enhanced Bcl-2 expression in the medial amygdaloid nucleus and ventromedial hypothalamus.
ECS Positive_regulation (enhanced) of Gene_expression (expression) of Bcl-2 in nucleus associated with convulsion
2) Confidence 0.01 Published 2008 Journal Neuropsychopharmacology Section Abstract Doc Link 17700647 Disease Relevance 1.02 Pain Relevance 0.67

General Comments

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