INT145993

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 4.40
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Xiap) nucleus (Xiap) intracellular (Xiap)
protein complex (Xiap) ligase activity (Xiap) cytoplasm (Xiap)
Anatomy Link Frequency
photoreceptors 1
Xiap (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sciatic nerve 9 96.64 Very High Very High Very High
Eae 3 91.36 High High
Gabapentin 2 84.88 Quite High
peripheral neuropathy 4 75.00 Quite High
Hyperalgesia 2 63.92 Quite High
allodynia 2 63.24 Quite High
chronic pain syndrome 2 62.16 Quite High
Pain 1 42.64 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 102 100.00 Very High Very High Very High
Targeted Disruption 9 94.00 High High
Retinal Degeneration 12 89.96 High High
Disease 13 80.76 Quite High
Neuropathic Pain 7 75.00 Quite High
Peripheral Neuropathy 6 75.00 Quite High
Hyperalgesia 2 63.92 Quite High
Retinal Diseases 3 62.96 Quite High
Complex Regional Pain Syndromes 2 62.16 Quite High
Muscle Weakness 2 59.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This protection correlates with the induction of X-linked inhibitor apoptosis protein (XIAP).
Positive_regulation (induction) of XIAP associated with apoptosis
1) Confidence 0.67 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17714181 Disease Relevance 1.31 Pain Relevance 0.51
This protection correlates with the induction of X-linked inhibitor apoptosis protein (XIAP).
Positive_regulation (induction) of X-linked inhibitor apoptosis protein associated with apoptosis
2) Confidence 0.60 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17714181 Disease Relevance 1.31 Pain Relevance 0.51
In our experience, increasing levels of XIAP have not had any deleterious effects on photoreceptors.
Positive_regulation (increasing) of XIAP in photoreceptors associated with apoptosis
3) Confidence 0.42 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819556 Disease Relevance 1.30 Pain Relevance 0
This protection correlates with the induction of XIAP.
Positive_regulation (induction) of XIAP
4) Confidence 0.42 Published 2009 Journal J. Neurosci. Res. Section Abstract Doc Link 19170187 Disease Relevance 0.49 Pain Relevance 0.13

General Comments

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