INT146024

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.06
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
arm 1
Ped (Mus musculus)
Pain Link Frequency Relevance Heat
Migraine 62 93.24 High High
abdominal pain 5 87.16 High High
Paresthesia 6 83.24 Quite High
Analgesic 4 73.20 Quite High
headache 19 70.48 Quite High
Inflammation 14 5.00 Very Low Very Low Very Low
Kinase C 9 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Endep 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinal Detachment 4 99.86 Very High Very High Very High
Cardiovascular Disease 21 99.76 Very High Very High Very High
Metabolic Syndrome 53 98.40 Very High Very High Very High
Sleep Disorders 5 96.96 Very High Very High Very High
Headache 80 93.24 High High
Disorder Of Lipid Metabolism 40 91.36 High High
Abdominal Pain 5 87.16 High High
Anorexia 6 84.28 Quite High
Dysesthesia 6 83.24 Quite High
Weight Loss 13 79.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Framingham 10-year CVD risk score decreased by 5.6% in the PED arm (P < 0.01) and 2.9% in the MED arm (P < 0.05).


Negative_regulation (decreased) of PED in arm associated with cardiovascular disease
1) Confidence 0.16 Published 2008 Journal Nutr Metab (Lond) Section Abstract Doc Link PMC2588603 Disease Relevance 1.10 Pain Relevance 0
OCT scans documented an improvement in neurosensory retinal detachment and a reduction of PED (Figures 1 and 2).
Negative_regulation (reduction) of PED associated with retinal detachment
2) Confidence 0.14 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2964964 Disease Relevance 0.46 Pain Relevance 0
The reduction in the PedMIDAS score indicates that the drug side effects (difficulties in concentrating, sedation) interfered with school, household or social activities to a lesser extent than the migraine episodes.
Negative_regulation (reduction) of PedMIDAS associated with migraine and sleep disorders
3) Confidence 0.02 Published 2008 Journal J Headache Pain Section Body Doc Link PMC2386848 Disease Relevance 0.98 Pain Relevance 0.67
There was a statistically significant decrease in the PedMIDAS score from 50.66 (+/-32.1) to 10.42 (+/-6.39) at the end of the study in the topiramate group compared with a decrease from 42.66 (+/-27.5) to 23.7 (+/-19.1) at the end of 4 months in the placebo group (P = .003).
Negative_regulation (decrease) of PedMIDAS
4) Confidence 0.01 Published 2007 Journal J. Child Neurol. Section Abstract Doc Link 17715274 Disease Relevance 0.52 Pain Relevance 0.45

General Comments

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