INT146045

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Context Info
Confidence 0.21
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.84
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Syt1) cytoplasm (Syt1)
Anatomy Link Frequency
caudate putamen 2
Syt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 2 94.48 High High
Spinal cord 3 93.84 High High
agonist 3 80.96 Quite High
Hippocampus 1 76.08 Quite High
Ventral tegmentum 1 75.44 Quite High
Substantia nigra 1 74.12 Quite High
Dopamine 1 64.24 Quite High
dopamine receptor 1 53.28 Quite High
Neurotransmitter 5 40.52 Quite Low
cytokine 18 35.60 Quite Low
Disease Link Frequency Relevance Heat
Periodontitis 30 100.00 Very High Very High Very High
Frailty 2 94.12 High High
Catalepsy 1 78.56 Quite High
Brain Injury 4 60.20 Quite High
Stress 7 59.28 Quite High
Alzheimer's Dementia 3 55.68 Quite High
Increased Venous Pressure Under Development 4 55.28 Quite High
Toxicity 8 54.40 Quite High
Alveolar Bone Loss 7 50.48 Quite High
INFLAMMATION 69 35.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of an Akt-specific inhibitor on expression of MafK, SytI, and Syn-1 genes in PC12 (WT-Akt) cells
Regulation (Effect) of Gene_expression (expression) of SytI
1) Confidence 0.21 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2844376 Disease Relevance 0.06 Pain Relevance 0
The reserpinization and/or apomorphine treatment had no effect on Syt 1 mRNA expression in caudate putamen.
Neg (no) Regulation (effect) of Gene_expression (expression) of Syt 1 mRNA in caudate putamen
2) Confidence 0.15 Published 2007 Journal Neurosci. Lett. Section Abstract Doc Link 17719177 Disease Relevance 0.08 Pain Relevance 0.36
B resides in the cytoplasm in an inactive form consisting of three subunits: p50 and p65 (constituting the factor dimer p50-p65) and the I?
Regulation (consisting) of Gene_expression (p50) of p65
3) Confidence 0.11 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3004876 Disease Relevance 0.32 Pain Relevance 0.05
Hypericum treatment significantly prevented the periodontitis-mediated NF-kB p65 expression (Figure 3b, b1).
Regulation (periodontitis) of Gene_expression (expression) of p65 associated with periodontitis
4) Confidence 0.10 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0.39 Pain Relevance 0

General Comments

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