INT146113

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adra2a, Lrp1) cytoplasm (Adra2a, Lrp1) cell proliferation (Lrp1)
endosome (Lrp1) signal transduction (Adra2a) nucleus (Lrp1)
Adra2a (Mus musculus)
Lrp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 2 99.28 Very High Very High Very High
Inflammation 4 89.68 High High
Sciatic nerve 1 88.04 High High
Peripheral nerve injury 3 87.28 High High
cytokine 5 78.96 Quite High
Neuropathic pain 1 55.84 Quite High
Disease Link Frequency Relevance Heat
Injury 3 98.44 Very High Very High Very High
Nervous System Injury 5 96.96 Very High Very High Very High
INFLAMMATION 4 89.68 High High
Death 1 84.44 Quite High
Toxicity 1 76.64 Quite High
Necrosis 1 73.00 Quite High
Cancer 1 72.64 Quite High
Neuropathic Pain 1 55.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When MAC was prepared using a mutated recombinant alpha2M, which does not bind to the alpha2M receptor, low-density lipoprotein receptor-related protein-1, activity in the chronic constriction injury model was blocked.
alpha2M Neg (not) Binding (bind) of receptor-related protein-1 associated with eae and injury
1) Confidence 0.01 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17725582 Disease Relevance 1.07 Pain Relevance 0.48

General Comments

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