INT1462

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Context Info
Confidence 0.49
First Reported 1978
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 1.50
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Lct) carbohydrate metabolic process (Lct)
Anatomy Link Frequency
plasma 1
small intestine 1
pole 1
Lct (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 1 99.62 Very High Very High Very High
aspirin 12 99.42 Very High Very High Very High
abdominal pain 1 98.52 Very High Very High Very High
Pain 7 98.16 Very High Very High Very High
Serotonin 6 90.08 High High
Inflammation 1 86.28 High High
agonist 1 85.84 High High
Potency 1 85.60 High High
cINOD 5 85.40 High High
dexamethasone 1 80.32 Quite High
Disease Link Frequency Relevance Heat
Diarrhoea 1 99.32 Very High Very High Very High
Abdominal Pain 1 98.52 Very High Very High Very High
Pain 6 98.16 Very High Very High Very High
Stress 1 97.82 Very High Very High Very High
Body Weight 2 96.80 Very High Very High Very High
Sleep Disorders 3 96.00 Very High Very High Very High
Syndrome 1 91.28 High High
Frailty 1 89.28 High High
Inflammatory Bowel Disease 1 86.84 High High
INFLAMMATION 3 84.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The formulation of MCT/LCT has a beneficial effect with respect to less pain on injection.
Positive_regulation (formulation) of LCT associated with pain
1) Confidence 0.49 Published 2005 Journal Anaesth Intensive Care Section Abstract Doc Link 15973918 Disease Relevance 0.42 Pain Relevance 0.18
After subcutaneous injection Met5-enkephalin appeared to be as active as ACTH 4-10 whereas beta-LPH 61-69, alpha- and beta-endorphin were more potent in delaying extinction of pole-jumping avoidance behavior (approximate ED50 of alpha-endorphin 4 x 10(-11) M rat.)
Positive_regulation (active) of LPH in pole associated with enkephalin
2) Confidence 0.49 Published 1978 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 204766 Disease Relevance 0 Pain Relevance 0.14
After 28 days, biochemical estimations in both drug treated groups showed an increase in sucrase, lactase, maltase and alkaline phosphatase as compared to the control.
Positive_regulation (increase) of lactase
3) Confidence 0.45 Published 2007 Journal Mol. Cell. Biochem. Section Abstract Doc Link 16855794 Disease Relevance 0.35 Pain Relevance 0.48
Immobilization stress (30 min) dramatically elevated plasma levels of both forms of immunoreactivity, however, a greater relative rise in beta-LPH than beta-END was observed.
Positive_regulation (rise) of beta-LPH in plasma associated with stress
4) Confidence 0.27 Published 1983 Journal Life Sci. Section Abstract Doc Link 6306375 Disease Relevance 0.10 Pain Relevance 0.38
TCI was conducted with Diprifusor for LCT and with BeComSim (custom-made software) for LCT/MCT.
Positive_regulation (conducted) of LCT
5) Confidence 0.27 Published 2006 Journal Acta Anaesthesiol Scand Section Body Doc Link 16643226 Disease Relevance 0.09 Pain Relevance 0
Aspirin and nimesulide exhibited an increase in the brush border membrane (BBM) bound enzyme activities like sucrase, lactase, maltase and alkaline phosphatase in the small intestine while celecoxib showed decrease in lactase, maltase and alkaline phosphatase.
Positive_regulation (increase) of lactase in small intestine associated with aspirin
6) Confidence 0.21 Published 2006 Journal Nutr Hosp Section Abstract Doc Link 17147060 Disease Relevance 0.07 Pain Relevance 0.28
Short-term TPN resulted in slightly lower lactase, sucrase, and palatinase activities that were not statistically different from controls.
Positive_regulation (resulted) of lactase
7) Confidence 0.05 Published 1993 Journal Dig. Dis. Sci. Section Abstract Doc Link 8359071 Disease Relevance 0.47 Pain Relevance 0.14

General Comments

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