INT146345

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc6a3) plasma membrane (Slc6a3) transmembrane transport (Slc6a3)
Anatomy Link Frequency
substantia nigra 2
Slc6a3 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 9 100.00 Very High Very High Very High
Substantia nigra 3 97.28 Very High Very High Very High
monoamine 2 89.36 High High
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 3 76.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tamoxifen at 50 microg reduced the methamphetamine effect on striatal dopamine concentration, dopamine transporter specific binding and prevented the increase in preproenkephalin mRNA levels; in the substantia nigra tamoxifen prevented the decrease of dopamine transporter mRNA levels.
Regulation (effect) of dopamine transporter Binding (binding) of in substantia nigra associated with dopamine and substantia nigra
1) Confidence 0.34 Published 2007 Journal Biochem. Pharmacol. Section Abstract Doc Link 17825264 Disease Relevance 0.22 Pain Relevance 0.61

General Comments

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