INT146463

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.45
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF10, NFKB1) nucleoplasm (NFKB1) mitochondrion (NFKB1)
cytoplasm (NFKB1) cell-cell signaling (TNFSF10) cytosol (NFKB1)
TNFSF10 (Homo sapiens)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 7 89.56 High High
fibrosis 3 89.32 High High
cytokine 1 86.28 High High
Inflammation 1 60.32 Quite High
cINOD 1 41.36 Quite Low
Disease Link Frequency Relevance Heat
Death 12 99.96 Very High Very High Very High
Pancreatitis 7 89.56 High High
Fibrosis 4 89.32 High High
Apoptosis 6 83.20 Quite High
Hypoglycemia 1 79.04 Quite High
Cancer 2 75.00 Quite High
Necrosis 2 75.00 Quite High
INFLAMMATION 2 60.32 Quite High
Primary Sclerosing Cholangitis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preceding cell death, TRAIL activated nuclear factor kappaB, c-Jun N-terminal kinase, p38 and p42/44.
TRAIL Positive_regulation (activated) of kappaB associated with death
1) Confidence 0.08 Published 2009 Journal FEBS J. Section Abstract Doc Link 19895579 Disease Relevance 1.01 Pain Relevance 0
TRAIL/ IFNgamma, upregulated NFkappaB subunits and survivin while down-modulating 1kappaBalpha.
TRAIL Positive_regulation (upregulated) of NFkappaB
2) Confidence 0.05 Published 2006 Journal Verh Dtsch Ges Pathol Section Abstract Doc Link 17867593 Disease Relevance 1.44 Pain Relevance 0.71

General Comments

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