INT146481

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Context Info
Confidence 0.61
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
synovial cells 2
HAS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 80.08 Quite High
Osteoarthritis 28 79.32 Quite High
Snapping jaw 3 79.28 Quite High
Inflammation 6 78.76 Quite High
Pain 16 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 2 81.56 Quite High
Cancer 2 81.20 Quite High
Osteoarthritis 36 79.32 Quite High
Temporomandibular Joint Syndrome 3 79.28 Quite High
INFLAMMATION 6 78.76 Quite High
Pain 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recklies et al. observed that the HAS1 message levels were always more abundant than that for HAS2 in synovial cells, and that the HAS3 message levels were always least abundant.
Gene_expression (abundant) of HAS2 in synovial cells
1) Confidence 0.61 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2553787 Disease Relevance 0.46 Pain Relevance 0.19
Recklies et al. observed that the HAS1 message levels were always more abundant than that for HAS2 in synovial cells, and that the HAS3 message levels were always least abundant.
Gene_expression (message) of HAS2 in synovial cells
2) Confidence 0.61 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2553787 Disease Relevance 0.46 Pain Relevance 0.19
The expression of HAS2 and 3 mRNA were enhanced about 4.2- and 7.2-fold after 4h stimulation with 1ng/ml of IL-1beta, respectively.
Gene_expression (expression) of HAS2
3) Confidence 0.52 Published 2008 Journal Arch. Oral Biol. Section Abstract Doc Link 17868639 Disease Relevance 0.16 Pain Relevance 0.24

General Comments

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