INT146566

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Context Info
Confidence 0.56
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 1.51
Pain Relevance 1.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Car2) extracellular space (Car2) lyase activity (Car2)
cytoplasm (Car2)
Anatomy Link Frequency
muscle 1
pore 1
brain 1
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 148 100.00 Very High Very High Very High
Gabapentin 1 94.48 High High
qutenza 1 93.20 High High
dorsal root ganglion 4 87.00 High High
antagonist 13 84.88 Quite High
Hyperalgesia 3 84.88 Quite High
nociceptor 2 83.40 Quite High
nMDA receptor antagonist 3 81.00 Quite High
Cancer pain 2 78.96 Quite High
nMDA receptor 10 76.60 Quite High
Disease Link Frequency Relevance Heat
Cancer 17 97.52 Very High Very High Very High
Fibrosarcoma 4 97.04 Very High Very High Very High
Ganglion Cysts 4 87.00 High High
Hyperalgesia 3 84.88 Quite High
Cancer Pain 2 78.96 Quite High
Sprains And Strains 5 75.28 Quite High
Adhesions 53 51.60 Quite High
Targeted Disruption 64 48.60 Quite Low
Alopecia 2 17.40 Low Low
Acantholysis 65 14.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Validation of BLI as an imaging modality for in vivo detection of Ca2+ transients during muscle contraction
Transcription (detection) of Ca2 in muscle associated with imagery
1) Confidence 0.56 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1991622 Disease Relevance 0 Pain Relevance 0.31
Non-invasive, high resolution in vivo detection of Ca2+ signals
Transcription (detection) of Ca2
2) Confidence 0.56 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1991622 Disease Relevance 0 Pain Relevance 0.13
Preparation of brain slices and in vitro detection of Ca2+-activities
Transcription (detection) of Ca2 in brain
3) Confidence 0.56 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1991622 Disease Relevance 0 Pain Relevance 0
Ca2+ imaging

[Ca2+]i was measured with a Ca2+ imaging system (Aquacosmos, Hamamatsu Photonics, Japan) mounted on an upright microscope (BX50WI, Olympus) using fura-2 and fura-4F (50 ?

Transcription (system) of Ca2 associated with imagery
4) Confidence 0.46 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2710870 Disease Relevance 0 Pain Relevance 0.16
The increased responses were associated with increased mRNA levels for the Ca2+ channel subunit alpha2delta1 and TRPV1 receptor.
Transcription (levels) of Ca2
5) Confidence 0.42 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17881535 Disease Relevance 1.38 Pain Relevance 0.78
Gmax at the peak of the Ca2+ current during the pre-pulse was 146 ± 12 pS/pF for controls, 172 ± 18 pS/pF ?
Transcription (peak) of Ca2
6) Confidence 0.31 Published 2001 Journal BMC Physiol Section Body Doc Link PMC37314 Disease Relevance 0 Pain Relevance 0.03
On the other hand, Chameau et al. [105] found by quantitative PCR that corticosterone did not change the mRNA expression of the pore-forming Cav1 subunit of the L-type Ca2+ channel, and ruled out transcriptional mechanisms in the effects they observed.
Transcription (expression) of Ca2 in pore
7) Confidence 0.09 Published 2010 Journal Mol Brain Section Body Doc Link PMC2841592 Disease Relevance 0.08 Pain Relevance 0.19
It was found that the Ca2+ concentration for half-maximal binding activity of Dsg 1 is 0.8 mM Ca2+ and that binding is highly cooperative with the Hill coefficient being ?
Transcription (found) of Ca2
8) Confidence 0.07 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.05 Pain Relevance 0

General Comments

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