INT146567

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.72
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2) extracellular region (Ccl2) cytoskeleton organization (Ccl2)
cytoplasm (Ccl2)
Anatomy Link Frequency
DRG 2
Ccl2 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 4 98.00 Very High Very High Very High
chemokine 1 97.40 Very High Very High Very High
Hyperalgesia 3 87.44 High High
Gabapentin 1 82.56 Quite High
Cancer pain 2 75.00 Quite High
qutenza 1 71.88 Quite High
nociceptor 2 62.08 Quite High
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 10 99.86 Very High Very High Very High
Ganglion Cysts 4 98.00 Very High Very High Very High
Fibrosarcoma 4 92.84 High High
Hyperalgesia 3 87.44 High High
Cancer Pain 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The CC chemokine ligand 2 (CCL2) may contribute to the tumor cell-induced sensitization because CCL2 immunoreactivity was present in tumors, high levels of CCL2 peptide were present in microperfusates from tumors, and treatment of DRG neurons in vitro with CCL2 increased the amount of mRNA for the alpha2delta1 subunit.
Negative_regulation (present) of Negative_regulation (levels) of CCL2 in DRG associated with dorsal root ganglion, chemokine and cancer
1) Confidence 0.43 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17881535 Disease Relevance 1.72 Pain Relevance 0.83

General Comments

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