INT146587

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.18
Pain Relevance 1.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Casp3) intracellular (Casp3) cytoplasm (Casp3)
cytosol (Casp3) extracellular space (Npff) peptidase activity (Casp3)
Npff (Rattus norvegicus)
Casp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 10 100.00 Very High Very High Very High
Eae 2 99.24 Very High Very High Very High
Opioid 8 90.80 High High
Neurotransmitter 2 88.80 High High
tolerance 2 81.52 Quite High
addiction 2 80.96 Quite High
antinociception 2 80.48 Quite High
Neuropeptide 4 76.56 Quite High
Disease Link Frequency Relevance Heat
Anxiety Disorder 2 96.04 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our experiments showed that NPFF, given intracerebroventricularly (i.c.v.) at the doses of 5, 10 and 20 nmol, inhibited the expression of morphine-induced CPP.
NPFF Negative_regulation (inhibited) of Positive_regulation (induced) of CPP associated with morphine
1) Confidence 0.05 Published 2007 Journal Peptides Section Abstract Doc Link 17884254 Disease Relevance 0.09 Pain Relevance 0.94
However, NPFF was unable to inhibit the expression of ethanol-induced CPP.
NPFF Negative_regulation (inhibit) of Neg (unable) Positive_regulation (induced) of CPP
2) Confidence 0.04 Published 2007 Journal Peptides Section Abstract Doc Link 17884254 Disease Relevance 0.10 Pain Relevance 0.98

General Comments

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