INT146711

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Hk2) carbohydrate metabolic process (Hk2) kinase activity (Hk2)
Anatomy Link Frequency
tubule 1
Hk2 (Mus musculus)
Pain Link Frequency Relevance Heat
isoflurane 11 98.48 Very High Very High Very High
antagonist 1 94.04 High High
Inflammation 4 90.84 High High
anesthesia 3 85.76 High High
ischemia 2 75.00 Quite High
positron emission tomography 24 41.84 Quite Low
imagery 5 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 3 97.56 Very High Very High Very High
INFLAMMATION 4 90.84 High High
Necrosis 4 87.72 High High
Renal Failure 1 87.20 High High
Hypoxia 1 82.80 Quite High
Cancer 100 82.00 Quite High
Cv Unclassified Under Development 2 75.00 Quite High
Reperfusion Injury 1 75.00 Quite High
Squamous Cell Neoplasms 1 50.00 Quite Low
Head & Neck Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared to the control group, high levels—though not statistically significant—of glucose transporter-1, HK II, and Ki67 expression were found at the end of treatment in both FDG and FLT groups.
Neg (not) Positive_regulation (levels) of HK II
1) Confidence 0.18 Published 2007 Journal Mol Imaging Biol Section Body Doc Link PMC2040178 Disease Relevance 0.62 Pain Relevance 0.05
SK activity as well as SK1 mRNA expression increased in both cultured human proximal tubule cells (HK-2) and mouse kidneys after exposure to isoflurane.
Positive_regulation (increased) of HK-2 in tubule associated with isoflurane
2) Confidence 0.11 Published 2007 Journal Am. J. Physiol. Renal Physiol. Section Abstract Doc Link 17898040 Disease Relevance 0.65 Pain Relevance 0.63

General Comments

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