INT146794

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Context Info
Confidence 0.50
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gla) extracellular region (Gla) Golgi apparatus (Gla)
lysosome (Gla) cytoplasm (Gla)
Anatomy Link Frequency
AGS 1
Gla (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 26.24 Quite Low
Pain 1 25.00 Low Low
Inflammation 11 19.84 Low Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alagille Syndrome 22 100.00 Very High Very High Very High
Stress 8 98.68 Very High Very High Very High
Stomach Cancer 22 92.28 High High
Anxiety Disorder 1 77.20 Quite High
Cancer 32 50.00 Quite Low
Necrosis 3 50.00 Quite Low
INFLAMMATION 14 19.84 Low Low
Infection 8 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Polyps 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results indicate that although reduced stress reactivity promotes exploration, this does not translate into an up-regulation of GLA, suggesting that the relationship between GLA and exploration is not mediated by stress reactivity.
Positive_regulation (up-regulation) of GLA associated with stress
1) Confidence 0.50 Published 2007 Journal Behav. Neurosci. Section Abstract Doc Link 17907827 Disease Relevance 0.66 Pain Relevance 0
stimulation in both AGS and Kato-III cells (Figure 5C).
Positive_regulation (stimulation) of AGS in AGS associated with alagille syndrome
2) Confidence 0.04 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.55 Pain Relevance 0

General Comments

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