INT146795

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Context Info
Confidence 0.62
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.36
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gla) extracellular region (Gla) Golgi apparatus (Gla)
lysosome (Gla) cytoplasm (Gla)
Gla (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 48 91.68 High High
Pain 2 25.00 Low Low
isoflurane 3 5.00 Very Low Very Low Very Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 16 99.76 Very High Very High Very High
Targeted Disruption 1 99.24 Very High Very High Very High
Anxiety Disorder 2 84.88 Quite High
Hepatocellular Cancer 1 56.24 Quite High
Carcinoma 2 52.96 Quite High
Pancreatic Cancer 47 50.00 Quite Low
Cancer 30 46.88 Quite Low
Pancreatitis 5 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding suggests the possibility that variations in stress reactivity modulate GLA and thus its relationship to exploratory tendencies.
Regulation (modulate) of GLA associated with stress
1) Confidence 0.62 Published 2007 Journal Behav. Neurosci. Section Abstract Doc Link 17907827 Disease Relevance 0.49 Pain Relevance 0
Results indicate that although reduced stress reactivity promotes exploration, this does not translate into an up-regulation of GLA, suggesting that the relationship between GLA and exploration is not mediated by stress reactivity.
Regulation (regulation) of GLA associated with stress
2) Confidence 0.27 Published 2007 Journal Behav. Neurosci. Section Abstract Doc Link 17907827 Disease Relevance 0.66 Pain Relevance 0
–galactosidase under the control of a ubiquitous ROSA-26 promoter [12].
Regulation (under) of galactosidase
3) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776527 Disease Relevance 0.21 Pain Relevance 0.05

General Comments

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