INT146813

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Context Info
Confidence 0.46
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.95
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ces1c) endoplasmic reticulum (Ces1c)
Anatomy Link Frequency
plasma 1
epididymis 1
Ces1c (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 2 94.08 High High
anesthesia 4 86.68 High High
Paracetamol 5 81.08 Quite High
Disease Link Frequency Relevance Heat
Myocardial Infarction 12 99.06 Very High Very High Very High
Body Weight 3 76.92 Quite High
Hepatotoxicity 1 75.00 Quite High
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Sperm Disorder 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Male Infertility 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low
Aggression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Q did not influence markedly on the severity of VA or rats mortality, while Z and Z+Q decreased mortality in rats in compare to II group of animals (from 68%-42% and 30%), increased the reduced BRS resulting from MI (+38.5% and +55.4%, p < 0.05) and blunted the increase of E1 (-34.8% and -43.5% respectively, p < 0.05).
Positive_regulation (increase) of E1 associated with myocardial infarction
1) Confidence 0.46 Published 2010 Journal Int J Clin Pharmacol Ther Section Abstract Doc Link 20420790 Disease Relevance 0.35 Pain Relevance 0.07
SO animals (0.92 +/- 0.14 ms/mmHg, p < 0.05) that correlated to increase E1 plasma concentration (9.2 +/- 0.6 pg/ml) vs.
Positive_regulation (increase) of E1 in plasma
2) Confidence 0.40 Published 2010 Journal Int J Clin Pharmacol Ther Section Abstract Doc Link 20420790 Disease Relevance 0.37 Pain Relevance 0.09
Results indicated that RSME reduced the levels of TBARS, SGOT and SGPT, and increased the level of GSH and the catalase activity in E1 and E2 as compared to the EC group.
Positive_regulation (increased) of E1
3) Confidence 0.33 Published 2007 Journal Br. J. Biomed. Sci. Section Abstract Doc Link 17910278 Disease Relevance 0.22 Pain Relevance 0.45
Testosterone replacement for the animals 7 days after castration resulted in a rapid increase in the serum testosterone concentration and the HongrES1 mRNA level in the epididymis (Figure 2B).
Positive_regulation (increase) of HongrES1 mRNA in epididymis
4) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2606034 Disease Relevance 0 Pain Relevance 0

General Comments

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