INT146845

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Tnf) enzyme binding (Trib3) extracellular matrix organization (Tnf)
extracellular space (Tnf) signal transduction (Tnf) extracellular region (Tnf)
Tnf (Rattus norvegicus)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 1 83.92 Quite High
Inflammation 1 78.12 Quite High
cytokine 1 75.16 Quite High
Disease Link Frequency Relevance Heat
Obesity 4 96.60 Very High Very High Very High
INFLAMMATION 2 83.72 Quite High
Cancer 2 75.00 Quite High
Necrosis 2 75.00 Quite High
Diabetes Mellitus 1 71.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To elucidate the cellular basis of this action, we show that salicylate suppresses TNF-alpha-induced extracellular signal-related kinase activation and intracellular cAMP elevation, two early events during the lipolysis response to TNF-alpha.
TNF-alpha Positive_regulation (induced) of Positive_regulation (activation) of kinase
1) Confidence 0.03 Published 2008 Journal Mol. Pharmacol. Section Abstract Doc Link 17911533 Disease Relevance 0.77 Pain Relevance 0.16

General Comments

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