INT146871

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.16
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tlr4, ROS1) cell differentiation (ROS1) cell proliferation (ROS1)
signal transduction (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)
Anatomy Link Frequency
leukocytes 2
neutrophils 2
Tlr4 (Mus musculus)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 20 99.22 Very High Very High Very High
Inflammation 20 93.44 High High
cytokine 11 90.88 High High
agonist 6 77.20 Quite High
Potency 1 27.60 Quite Low
antagonist 6 25.00 Low Low
cINOD 1 25.00 Low Low
Inflammatory response 5 12.88 Low Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 11 95.96 Very High Very High Very High
INFLAMMATION 25 93.44 High High
Stress 12 90.40 High High
Hyperplasia 1 89.84 High High
Necrosis 5 75.00 Quite High
Cancer 5 75.00 Quite High
Apoptosis 16 51.04 Quite High
Pneumonia 4 50.00 Quite Low
Injury 2 23.60 Low Low
Death 2 20.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the addition of this compound to cultured pneumocytes was found to reduce the LPS-induced generation of ROS and the activation of mitogen-activated protein kinases and Bax [29]; and the pretreatment of rats with 5% TAU in the drinking water resulted in a lower number of inflammatory leukocytes infiltrating the lung and in attenuation of the focal bronchiolar hyperplasia that developed from a short contact with ozone [30].
LPS Positive_regulation (induced) of Gene_expression (generation) of ROS in leukocytes associated with inflammation and hyperplasia
1) Confidence 0.00 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994390 Disease Relevance 0.86 Pain Relevance 0.12
The results of previous studies indicate that adenosine analogues inhibit lipopolysaccharide (LPS)-induced production of reactive oxygen species (ROS) by equine neutrophils primarily through activation of A2A receptors.
LPS Positive_regulation (induced) of Gene_expression (production) of ROS in neutrophils associated with adenocard
2) Confidence 0.00 Published 2008 Journal Vet. Immunol. Immunopathol. Section Abstract Doc Link 17913243 Disease Relevance 0.30 Pain Relevance 0.44

General Comments

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