INT146995

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.14
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NPR2) plasma membrane (NPR2)
Anatomy Link Frequency
muscle 2
esophagus 1
NPR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 6 88.48 High High
agonist 3 68.84 Quite High
Disease Link Frequency Relevance Heat
Natriuresis 33 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results demonstrate that natriuretic peptides cause relaxation of the muscularis mucosae of the human esophagus and suggest that the relaxation is through interaction with NPR-B.
NPR-B Binding (interaction) of in esophagus associated with natriuresis
1) Confidence 0.43 Published 2008 Journal Regul. Pept. Section Abstract Doc Link 17920706 Disease Relevance 0.63 Pain Relevance 0.21
Natriuretic peptides have been demonstrated to cause relaxation of the human gallbladder muscle through interaction with natriuretic peptide receptor-B (NPR-B/NPR2).
NPR-B Binding (interaction) of in muscle associated with natriuresis
2) Confidence 0.43 Published 2008 Journal Regul. Pept. Section Abstract Doc Link 17920706 Disease Relevance 0.76 Pain Relevance 0.03
Natriuretic peptides have been demonstrated to cause relaxation of the human gallbladder muscle through interaction with natriuretic peptide receptor-B (NPR-B/NPR2).
NPR2 Binding (interaction) of in muscle associated with natriuresis
3) Confidence 0.35 Published 2008 Journal Regul. Pept. Section Abstract Doc Link 17920706 Disease Relevance 0.76 Pain Relevance 0.03

General Comments

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