INT147107

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 0.67
Pain Relevance 2.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TGFB1, NGF) extracellular region (TGFB1, NGF) endosome (NGF)
aging (TGFB1) enzyme binding (TGFB1) embryo development (TGFB1)
Anatomy Link Frequency
nerve 4
dental pulp 2
TGFB1 (Homo sapiens)
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 24 100.00 Very High Very High Very High
dexamethasone 32 99.92 Very High Very High Very High
Pain 4 88.72 High High
Disease Link Frequency Relevance Heat
Injury 8 98.60 Very High Very High Very High
Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The application of both TGF-beta1 and dexamethasone resulted in an additional effect on fibronectin; however, dexamethasone inhibited the TGF-beta1-induced NGF expression.
TGF-beta1-induced Positive_regulation (induced) of Gene_expression (expression) of NGF associated with nerve growth factor and dexamethasone
1) Confidence 0.49 Published 2007 Journal J Endod Section Abstract Doc Link 17931932 Disease Relevance 0.15 Pain Relevance 0.71
TGF-beta1 increased expression and synthesis of both fibronectin and nerve growth factor (NGF), whereas dexamethasone stimulated fibronectin synthesis but inhibited NGF expression.
TGF-beta1 Positive_regulation (increased) of Gene_expression (expression) of nerve growth factor in nerve associated with nerve growth factor and dexamethasone
2) Confidence 0.49 Published 2007 Journal J Endod Section Abstract Doc Link 17931932 Disease Relevance 0.17 Pain Relevance 0.68
TGF-beta1 increased expression and synthesis of both fibronectin and nerve growth factor (NGF), whereas dexamethasone stimulated fibronectin synthesis but inhibited NGF expression.
TGF-beta1 Positive_regulation (increased) of Gene_expression (expression) of NGF in nerve associated with nerve growth factor and dexamethasone
3) Confidence 0.49 Published 2007 Journal J Endod Section Abstract Doc Link 17931932 Disease Relevance 0.17 Pain Relevance 0.69
Different roles of dexamethasone on transforming growth factor-beta1-induced fibronectin and nerve growth factor expression in dental pulp cells.
transforming growth factor-beta1 Positive_regulation (induced) of Gene_expression (expression) of nerve growth factor in dental pulp associated with nerve growth factor and dexamethasone
4) Confidence 0.40 Published 2007 Journal J Endod Section Title Doc Link 17931932 Disease Relevance 0.19 Pain Relevance 0.60

General Comments

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