INT147147

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CDKN2A) DNA binding (CDKN2A) protein complex (CDKN2A)
cytoplasm (CDKN2A) cytosol (CDKN2A) nucleolus (CDKN2A)
CDKN2A (Homo sapiens)
Pain Link Frequency Relevance Heat
Cannabinoid 4 5.00 Very Low Very Low Very Low
cannabis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Delta-9-tetrahydrocannabinol 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioblastoma 2 50.00 Quite Low
Cancer 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cell content of E2F1 and Cyclin A, two proteins that promote cell cycle progression, were suppressed in both U251-MG and U87-MG human glioblastoma cell lines, whereas the level of p16(INK4A), a cell cycle inhibitor was upregulated.
Positive_regulation (upregulated) of Transcription (level) of INK4A
1) Confidence 0.49 Published 2008 Journal Acta Oncol Section Body Doc Link 17934890 Disease Relevance 0 Pain Relevance 0
The cell content of E2F1 and Cyclin A, two proteins that promote cell cycle progression, were suppressed in both U251-MG and U87-MG human glioblastoma cell lines, whereas the level of p16(INK4A), a cell cycle inhibitor was upregulated.
Positive_regulation (upregulated) of Transcription (level) of p16
2) Confidence 0.23 Published 2008 Journal Acta Oncol Section Body Doc Link 17934890 Disease Relevance 0 Pain Relevance 0

General Comments

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