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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.85
Pain Relevance 1.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abcc2) ATPase activity (Abcc2) transmembrane transport (Abcc2)
Abcc2 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 11 99.56 Very High Very High Very High
diclofenac 10 99.02 Very High Very High Very High
Analgesic 1 96.28 Very High Very High Very High
Inflammation 1 95.52 Very High Very High Very High
Bile 1 94.96 High High
Perioperative pain 1 93.60 High High
rheumatoid arthritis 1 92.80 High High
Cancer pain 1 91.44 High High
methotrexate 1 61.08 Quite High
Disease Link Frequency Relevance Heat
Breast Cancer 3 99.36 Very High Very High Very High
INFLAMMATION 1 95.52 Very High Very High Very High
Post Operative Pain 1 93.60 High High
Rheumatoid Arthritis 1 92.80 High High
Cancer Pain 1 91.44 High High
Hepatotoxicity 4 75.00 Quite High
Cancer 2 32.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, multidrug resistance-associated proteins Mrp1, Mrp2, Mrp3, and Mrp4, as well as multidrug resistance proteins Mdr1a and Mdr1b genes, were increased following APAP.
Positive_regulation (increased) of Mrp2 associated with paracetamol
1) Confidence 0.39 Published 2007 Journal J. Toxicol. Environ. Health Part A Section Abstract Doc Link 17934960 Disease Relevance 0.30 Pain Relevance 0.88
Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benzbromarone.
Positive_regulation (stimulation) of multidrug resistance protein 2 associated with breast cancer and diclofenac
2) Confidence 0.22 Published 2009 Journal Drug Metab. Dispos. Section Title Doc Link 18845662 Disease Relevance 0.54 Pain Relevance 0.76

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