INT147160

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.95
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abcc3) ATPase activity (Abcc3) transmembrane transport (Abcc3)
Abcc3 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 11 98.28 Very High Very High Very High
Bile 1 39.84 Quite Low
aspirin 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 7 95.56 Very High Very High Very High
Disorder Of Lipid Metabolism 33 86.72 High High
Hypertriglyceridemia 12 64.32 Quite High
Dyslipidemia /

Combined Dyslipidemia

14 50.00 Quite Low
Diabetes Mellitus 10 47.44 Quite Low
Metabolic Syndrome 8 46.96 Quite Low
Increased Venous Pressure Under Development 22 43.92 Quite Low
Obesity 5 34.20 Quite Low
Breast Cancer 1 25.00 Low Low
Atherosclerosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies demonstrated differential expression of hepatobiliary transporter mRNA in mice treated with a toxic dose of APAP dissolved in 50% propylene glycol.
Transcription (expression) of transporter associated with paracetamol
1) Confidence 0.42 Published 2007 Journal J. Toxicol. Environ. Health Part A Section Abstract Doc Link 17934960 Disease Relevance 0.25 Pain Relevance 0.66
Both cholesterol efflux and the transcription of efflux-related receptors, namely CD36 and ATP-binding cassette protein A1, were increased by niacin.
Transcription (transcription) of ATP-binding cassette protein
2) Confidence 0.25 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605342 Disease Relevance 0.69 Pain Relevance 0

General Comments

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