INT147179

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Esr1) DNA binding (Esr1) protein complex (Esr1)
cytoplasm (Esr1) lipid binding (Esr1) extracellular region (Penk)
Esr1 (Mus musculus)
Penk (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 4 100.00 Very High Very High Very High
Dopamine 3 93.20 High High
nMDA receptor 1 86.56 High High
Glutamate 1 81.84 Quite High
opiate 1 81.28 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 99.08 Very High Very High Very High
Parkinson's Disease 2 95.28 Very High Very High Very High
Toxicity 2 94.88 High High
Apoptosis 1 88.64 High High
Cancer 1 78.60 Quite High
Neurodegenerative Disease 1 73.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both ERalpha and ERbeta agonists modulate striatal preproenkephalin (PPE) gene expression in ovariectomized rats.
ERalpha Regulation (modulate) of Gene_expression (expression) of striatal preproenkephalin associated with agonist
1) Confidence 0.01 Published 2008 Journal J. Steroid Biochem. Mol. Biol. Section Abstract Doc Link 17936613 Disease Relevance 0.68 Pain Relevance 0.46

General Comments

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